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| Serakides,R.; Nunes,V.A; Nascimento,E.F.; Serra,G.V.. |
| The influence of the estrous cycle on the thyroid gland was studied. Twenty one five-to-seven-month-old Wistar female rats were divided according to the stage of the estrous cycle in two groups: metaestrus-diestrus and proestrus-estrus. After gross inspection, the thyroids were weighed, sampled, and processed for staining with hematoxilyn-eosin. Seric concentrations of total T4, free T4, total T3, TSH, progesterone, and estradiol were measured. The values of estradiol were significantly higher in the proestrus-estrus stage. However, no significant differences in the plasmatic concentrations of progesterone, free T4, total T4 and TSH throughout the cycle were found. The results of the morphometric study of the thyroid did not indicate any significant... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Rat; Thyroid; Estrous cycle. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000100017 |
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| Ferreira,E.; Serakides,R.; Nunes,V.A; Gomes,M.G.; Silva,C.M.; Ocarino,N.M.; Ribeiro,A.F.C.. |
| Foram estudadas as alterações cutâneas de ratas Wistar adultas castradas e não castradas, mantidas em estado hipotireóideo por 120 dias. Dois grupos eutireóideos, um castrado e outro não castrado, serviram de controle. Secções da pele abdominal ventral e torácica dorsal foram coradas pelas técnicas de HE, PAS, azul de alcian (alcian blue), picro-sirius red-luz polarizada e Verhoeff. Adelgaçamento da epiderme, atrofia de glândulas sebáceas, redução parcial ou total de fibras elásticas e do colágeno do tipo III da derme caracterizaram tanto o hipotireoidismo quanto a castração. Retardo no crescimento dos folículos pilosos e hiperceratose foram vistos apenas na deficiência dos hormônios tireoidianos, independente do estado funcional das gônadas. A associação... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rata; Pele; Hipotireoidismo; Castração. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000100008 |
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| Silva,C.M.; Serakides,R.; Nascimento,E.F.; Nunes,V.A; Ribeiro,A.F.C.; Ocarino,N.M.. |
| The goal of this study was to determine whether the quantification of the nucleolar organizer regions (AgNORs) is a useful parameter for evaluation of the proliferative potential of non-neoplastic granulosa cells in ovarian follicles at different stages of development. Seven ovaries from six-month-old rats, all of which in metestrus-diestrus, were studied. The number of AgNORs from 60 granulosa cell nuclei was quantified in secondary follicles with two to three layers of cells and in follicles with more than five layers of granulosa cells. Follicles with two to three layers had larger AgNORs in lower numbers, whereas more developed secondary follicles the AgNORs were predominantly smaller, scattered throughout the nucleus, and in significantly higher... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rato; Oócito; Célula da granulosa; AgNORs. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000100019 |
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